Donovanosis =الحبيبوم المغبني=الداء الدونوفاني
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چکیده
Granuloma inguinale is a chronic bacterial infection that frequently is associated with other sexually transmitted diseases. Granuloma inguinale is characterized by intracellular inclusions in macrophages referred to as Donovan bodies. Granuloma inguinale usually affects the skin and mucous membranes in the genital region, where it results in nodular lesions that evolve into ulcers. The ulcers progressively expand and are locally destructive
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TROPICAL MEDICINE SERIES Donovanosis
Donovanosis, a chronic cause of genital ulceration, has recently been the subject of renewed interest after a long period of relative obscurity. The causative organism, Calymmatobacterium granulomatis, has been cultured for the first time in many years and a polymerase chain reaction diagnostic using a colorimetric detection system has been developed. Phylogenetic analysis confirms close simila...
متن کاملNodal Donovanosis as the Sentinel Clue to Acquired Immunodeficiency Syndrome
Objective: Donovanosis, caused by Calymmatobacterium granulomatis, is a recognized cause of genital ulcer disease. Extragenital donovanosis in acquired immunodeficiency syndrome (AIDS) and lymph nodes is documented rarely. The aim of this report is to highlight implications of lymph node involvement as the initial manifestation of donovanosis, especially in AIDS. Materials and methods: This is ...
متن کاملClinico-epidemiological study of donovanosis in Durban, South Africa.
OBJECTIVE To describe the epidemiological and clinical features of donovanosis and their relevance to the possible coincident risk of HIV-1 transmission in patients attending an STD clinic. DESIGN Assessment of patients with donovanosis diagnosed by the detection of Donovan bodies on tissue smears stained by the RapiDiff technique. SETTING City Health STD Clinic, King Edward VIII Hospital, ...
متن کاملSexually transmitted diseases in South Africa: epidemic donovanosis in Durban?
Sexually transmitted diseases in South Africa: epidemic donovanosis in Durban? In their review of sexually transmitted diseases in South Africa, Pham-Kanter and colleagues state that donovanosis may have disappeared only to reemerge in 1981 in Johannesburg, with subsequent case reports from other areas including Durban.' This scenario is exceedingly unlikely if the Annual reports of the Medical...
متن کاملExtragenital donovanosis in a patient with AIDS.
A case of extragenital donovanosis in a patient with AIDS is reported from Zimbabwe. Despite the rarity of donovanosis in Zimbabwe it is important that health workers are familiar with this disease since donovanosis increases the risk of HIV transmission and appropriate treatment is often successful even in patients with severe immunodeficiency.
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